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Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S Suppression of hepcidin during anemia requires erythropoietic activity.
Blood
2006; 108(12):
3730-5.
Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T
The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study.
Blood
2006; 107(1):
328-33.
Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dube MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR, Goldberg YP Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.
Nat Genet.
2004; 36(1):
77-82.
Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein (Plenary Article).
Blood.
2003; 101:
2461-2463.
Sham Ronald L, Phatak Pradyumna D, Nemeth Elizabeta, Ganz Tomas Hereditary hemochromatosis due to resistance to hepcidin: high
hepcidin concentrations in a family with C326S ferroportin mutation..
Blood.
2009; 114(2):
493-4.
Fernandes Augustine, Preza Gloria C, Phung Yen, De Domenico Ivana, Kaplan Jerry, Ganz Tomas, Nemeth Elizabeta The molecular basis of hepcidin-resistant hereditary hemochromatosis..
Blood.
2009; 114(2):
437-43.
Ganz Tomas, Olbina Gordana, Girelli Domenico, Nemeth Elizabeta, Westerman Mark Immunoassay for human serum hepcidin..
Blood.
2008; 112(10):
4292-7.
Ganz Tomas Iron homeostasis: fitting the puzzle pieces together..
Cell metabolism.
2008; 7(4):
288-90.
Valore Erika V, Ganz Tomas Posttranslational processing of hepcidin in human hepatocytes is
mediated by the prohormone convertase furin..
Blood cells, molecules & diseases.
2008; 40(1):
132-8.
Lin Lan, Nemeth Elizabeta, Goodnough Julia B, Thapa Dharma R, Gabayan Victoria, Ganz Tomas Soluble hemojuvelin is released by proprotein convertase-mediated
cleavage at a conserved polybasic RNRR site..
Blood cells, molecules & diseases.
2008; 40(1):
122-31.
Lin Lan, Valore Erika V, Nemeth Elizabeta, Goodnough Julia B, Gabayan Victoria, Ganz Tomas Iron transferrin regulates hepcidin synthesis in primary hepatocyte
culture through hemojuvelin and BMP2/4..
Blood.
2007; 110(6):
2182-9.
Lin L, Goldberg YP, Ganz T Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin..
Blood. .
2005; 106(8):
2884-9.
Linzmeier RM, Ganz T Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23..
Genomics..
2005; 86(4):
423-30.
Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs..
Blood. .
2005; 106(6):
2196-9.
Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia..
Blood. .
2005; 105(4):
1797-802.
Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C Hepcidin is decreased in TFR2 hemochromatosis..
Blood. .
2005; 105(4):
1803-6.
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization..
Science. .
2004; 306(5704):
2090-3.
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin..
The Journal of clinical investigation. .
2004; 113(9):
1271-6.
Ganz T Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation..
Blood. .
2003; 102(3):
783-8.
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