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Stephen Young, M.D.
Affiliations
Professor, Medicine, Human Genetics
Administrator, ACCESS Program: Dept. of Human Genetics
Faculty, Cardiology
Education:
Medical Degree: M.D., University of Gothenburg, Sweden
Certification Type: Professional Affiliation, Certified, American Board of Clinical Lipidology
Medical Degree: M.D., Washington University School of Medicine, 1978
Certifications:
Medical Board Certification: Cardiovascular Disease, American Board of Internal Medicine, 1983
Internal Medicine, American Board of Internal Medicine, 1981
Contact Information:
Work Email Address: sgyoung@mednet.ucla.edu
Department Address: Office
Mailcode: 167917
Los Angeles, CA 90095
UNITED STATES
Mailing Address: Office
675 Charles E. Young Drive South
Los Angeles, CA 90095
UNITED STATES
Direct Contact Information:
Fax Number: (310) 206-0865 Fax
Office Phone Number: (310) 825-4934 Office
Additional Information:

Stephen Young grew up in Kansas and obtained an undergraduate degree in history from Princeton University. Following medical school at Washington University-St. Louis, internal medicine training at UCSF, and cardiology training at UCSD, he embarked on a career in basic science, focusing on the molecular genetics of human disease. He did postdoctoral research training in lipid metabolism at UCSD and then worked at a research institute at UCSF for 17 years. Along the way, he became an expert in using genetically modified mice to decipher gene function. Currently, his laboratory works on protein posttranslational modifications, diseases of the nuclear lamina, and a new molecule that controls the plasma levels of triglycerides. His laboratory has a strong track record in developing the careers of young scientists.

Publications:
Weinstein MM, Yin L, Beigneux AP, Davies BS, Gin P, Estrada K, Melford K, Bishop JR, Esko JD, Dallinga-Thie GM, Fong LG, Bensadoun A, Young SG. Abnormal patterns of lipoprotein lipase release into the plasma in GPIHPB1-deficient mice . J. Biol. Chem. ; 12: 34511–34518.
Beigneux AP, Davies BS, Gin P, Weinstein MM, Farber E, Qiao X, Peale F, Bunting S, Walzem RL, Wong JS, Blaner WS, Ding ZM, Melford K, Wongsiriroj N, Shu X, de Sauvage F, Ryan RO, Fong LG, Bensadoun A, Young SG. Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons.. Cell Metabolism ; 5: 279–291.
Coffinier C, Hudon SE, Farber EA, Chang SY, Hrycyna CA, Young SG, Fong LG. HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells. Proc. Natl. Acad. Sci. USA ; 104: 13432-13437.
Yang SH, Andres DA, Spielmann HP, Young SG, and Fong LG. Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.. J. Clin. Invest. 2008; 118: 3291-3300.
Gin P, Yin L, Davies BSJ, Weinstein MM, Ryan RO, Bensadoun A, Fong LG, Young SG, and Beigneux AP The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol. Chem 2008; 283: 29554-29562.


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